700027P

7α-hydroxy-3-oxo-4-cholestenoic acid

Manufacturer: Sigma Aldrich

CAS Number: 1246298-65-6

Synonym(S): (25R)-cholest-4-en-26-oic acid, 7α-hydroxy-3-oxo

Select a Size

Pack Size SKU Availability Price
1 MG 700027P-1-MG In Stock ₹ 57,307.55

700027P - 1 MG

₹ 57,307.55

In Stock

Quantity

1

Base Price: ₹ 57,307.55

GST (18%): ₹ 10,315.359

Total Price: ₹ 67,622.909

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700027P-1mg)

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

storage temp.

−20°C

Other Options

Image Product Name Manufacturer Price Range
Cholesterol Impurity 40
-- --
1246298-65-6 | (25R)-cholest-4-en-26-oic acid, 7α-hydroxy-3-oxo
-- ₹ 1,69,100.00

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Description

  • General description: 7α-Hydroxy-3-oxo-4-cholestenoic acid (7-HOCA) is synthesized extrahepatically from cholesterol.[1] The enzyme oxysterols-7α-hydrolase (CYP7B1) acts on precursor 27-hydroxycholesterol (27-OHC) to generate 7-HOCA.[2]. 7-HOCA is catabolized in the liver.[3]
  • Application: 7α-hydroxy-3-oxo-4-cholestenoic acid has been used as an analyte in ultra-high-performance liquid chromatography (UHPLC) system.[4]
  • Biochem/physiol Actions: The levels of 7α-hydroxy-3-oxo-4-cholestenoic acid (7-HOCA) in cerebrospinal fluid are not correlated to neurodegeneration but may serve as a diagnostic marker to trace blood-brain barrier integrity.[1]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (700027P-1mg)