700058P
22(R)-hydroxycholesterol
Manufacturer: Sigma Aldrich
CAS Number: 17954-98-2
Synonym(S): 5-cholestene-3β,22-diol; 22-hydroxycholest-5-en-3-ol
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | 700058P-1-MG | In Stock | ₹ 15,382.33 |
| 5 MG | 700058P-5-MG | In Stock | ₹ 54,687.90 |
700058P - 1 MG
In Stock
Quantity
1
Base Price: ₹ 15,382.33
GST (18%): ₹ 2,768.819
Total Price: ₹ 18,151.149
description
cholest-5-ene-3β,22(R)-diol
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700058P-1mg)pkg of 1 × 5 mg (700058P-5mg)
manufacturer/tradename
Avanti Polar Lipids
shipped in
dry ice
storage temp.
−20°C
InChI
1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25+,26-,27+/m0/s1
InChI key
RZPAXNJLEKLXNO-GFKLAVDKSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
22(R)-Hydroxycholesterol | -- | ₹ 10,424.48 - ₹ 40,279.83 | ||
22(R)-Hydroxycholesterol | -- | ₹ 6,764.00 - ₹ 46,280.00 | ||
17954-98-2 | (8S,9S,10R,13S,14S,17R)-17-((2S,3R)-3-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol | -- | ₹ 4,895.00 - ₹ 37,558.00 |
Related Products
Description
- General description: 22(R)-hydroxycholesterol is a diastereomer of 22(S)-hydroxycholesterol.[1] It is present in neonate brain.[2]
- Application: 22(R)-hydroxycholesterol has been used as a liver X receptor (LXR) ligand in breast cancer cell lines.[3] It may be used as an internal standard to spike mouse brain tissue samples for ultra-performance liquid chromatography–high resolution mass spectrometry (UPLC-ESI-HRMS) analysis.[4]
- Biochem/physiol Actions: 22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand.[5]. 22(R)-HC in combination with other oxysterols promote mesenchymal stem cell osteogenesis.[6] It regulates cholesterol homeostasis.[7] Low levels of 22(R)-HC is observed in Alzheimer′s disease and it may be implicated in neuroinflammation and neurodegenerative diseases.[2] 22(R)-hydroxycholesterol also suppresses prostate tumor progression.[8]
- Packaging: 5 mL Amber Glass Screw Cap Vial (700058P-1mg)
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable