Description

• General description: Myricetin (MYR) is a natural polyhydroxyflavonol compound, first isolated from the bark of Morella rubra (Myrica rubra) tree.[1]
• Application: Myricetin has been used:to study its preventive effect as an antioxidant on noise-induced hearing loss (NIHL) in rats[2]as a flavonoid compound to test antiviral activity of Bourbon virus (BRBV) and in inhibition of RNA-dependent RNA polymerase (RdRP)[3]to study its effect as a treatment on biofilms of Streptococcus mutans and Candida albicans[4]as a reference standard for the quantification of phenolic compounds from Juniperus species[5]
• Biochem/physiol Actions: Myricetin exerts anti-oxidant effects[6], and anti-inflammatory effects by regulating multiple signal pathways.[1] It also displays anti-diabetic[1] and hepatoprotective effects.[6] Myricetin strongly inhibits yeast α-glucosidase,[7] glyoxalase I in vitro,[8] and bovine milk xanthine oxidase.[9] It also promotes complex formation between DNA and both topoisomerase I and II, an effect that may have implications in cancer chemotherapy.[10] Myricetin also has various nutraceuticals values and therapeutic effects.[1][6]