860504P

C4 Ceramide (d18:1/4:0)

Manufacturer: Sigma Aldrich

CAS Number: 74713-58-9

Synonym(S): N-butyroyl-D-erythro-sphingosine

Select a Size

Pack Size SKU Availability Price
5 MG 860504P-5-MG In Stock ₹ 12,557.00

860504P - 5 MG

₹ 12,557.00

In Stock

Quantity

1

Base Price: ₹ 12,557.00

GST (18%): ₹ 2,260.26

Total Price: ₹ 14,817.26

form

powder

packaging

pkg of 1 × 5 mg (860504P-5mg)

manufacturer/tradename

Avanti Polar Lipids 860504P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C22H43NO3/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-18-21(25)20(19-24)23-22(26)17-4-2/h16,18,20-21,24-25H,3-15,17,19H2,1-2H3,(H,23,26)/b18-16+/t20-,21+/m0/s1

InChI key

UCBLGIBMIAFISC-CQLAPORSSA-N

Other Options

Image Product Name Manufacturer Price Range
eMolecules​ Broadpharm / C4 Ceramide / 10mg / 779523902 / BP-28806 / / 74713-58-9 / MFCD02259135 / 369.590 / C22H43NO3
-- ₹ 14,636.05
74713-58-9 | C4 Ceramide
-- ₹ 5,073.00 - ₹ 42,720.00

Description

  • General description: C4 Ceramide (d18:1/4:0) or N-butyroyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with butyric acid. It is a non-toxic, short-chain sphingolipid.[1]
  • Application: C4 Ceramide (d18:1/4:0) has been used to study its role in rescuing and stabilizing ΔF508-cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR).[1]
  • Biochem/physiol Actions: C4 Ceramide (d18:1/4:0) is implicated in a series of mutual autophosphorylation and phosphorylation actions between 3-phosphoinositide-dependent kinase 1 (PDK1) and serum/glucocorticoid-induced protein kinase 1 (SGK1). It stimulates cyclic adenosine monophosphate (cAMP)-activated chloride secretion and represses hypersecretion of interleukin-8 (IL-8). C4 Ceramide might be a potential therapeutic for cystic fibrosis (CF).[1]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860504P-5mg)

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable