860537P
Galactosyl(β) Sphingosine (d18:1)
Manufacturer: Sigma Aldrich
CAS Number: 2238-90-6
Synonym(S): D-galactosyl-β1-1′-D-erythro-sphingosine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 860537P-5-MG | In Stock | ₹ 40,777.78 |
860537P - 5 MG
In Stock
Quantity
1
Base Price: ₹ 40,777.78
GST (18%): ₹ 7,340.00
Total Price: ₹ 48,117.78
form
powder
packaging
pkg of 1 × 25 mg (860537P-25mg)pkg of 1 × 5 mg (860537P-5mg)
manufacturer/tradename
Avanti Polar Lipids 860537P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@](N)([H])CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O
InChI
1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21-,22-,23+,24+/m0/s1
InChI key
HHJTWTPUPVQKNA-PIIMIWFASA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Sigma Aldrich Fine Chemicals Biosciences Psychosine from bovine brain lyophilized powder, >=98% (TLC) | 2238-90-6 | MFCD00057505 | 10MG | -- | ₹ 55,536.00 | ||
Cayman Chemical Galactosylsphingosine (d18:1), 2238-90-6, 1 mg | -- | ₹ 6,448.05 | ||
Psychosine from bovine brain | -- | ₹ 11,106.45 - ₹ 37,984.93 | ||
2238-90-6 | Psychosine | -- | ₹ 5,073.00 - ₹ 26,878.00 |
Related Products
Description
- General description: Galactosyl(β) Sphingosine (d18:1) is a substrate for the enzyme endoglycoceramidase I (EGCase I). It has sphingosine backbone with galactose attached to it and is a brain glycospingolipid.[1]
- Application: Galactosyl(β) Sphingosine (d18:1) has been used in the liposome preparation for α-synuclein aggregation studies.[2] It is suitable for use to test its inhibitory effect on cytokinesis in cells expressing T-cell death-associated gene 8 (TDAG8).[3] It is also suitable for use as a standard for differential mobility spectrometry (DMS) coupled with liquid chromatography in electrospray ionizatoin tandem mass spectrometry (LC-ESI-DMS-MS/MS) for ceramide quantification[4] and ultra-high resolution ion mobility spectrometry measurments.[5]
- Biochem/physiol Actions: Galatosylsphingosine or psychosine is a cytotoxic lipid which accumulates in oligodendrocytes due to dysfunctional lysosomal enzyme galactosylceramidase and is implicated in globoid cell leukodystrophy.[6] Psychosine accumulation induces demyelination, astrocyte dysfunction and pro-inflammatory cytokine release in Krabbe disease.[7]
- Packaging: 5 mL Amber Glass Screw Cap Vial (860537P-25mg)
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable