860654P
sphinganine (d17:0)
Manufacturer: Sigma Aldrich
CAS Number: 32164-02-6
Synonym(S): D-erythro-sphinganine (C17 base)
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 860654P-5-MG | In Stock | ₹ 27,831.08 |
| 10 MG | 860654P-10-MG | In Stock | ₹ 48,625.90 |
860654P - 5 MG
In Stock
Quantity
1
Base Price: ₹ 27,831.08
GST (18%): ₹ 5,009.594
Total Price: ₹ 32,840.674
form
powder
packaging
pkg of 1 × 10 mg (860654P-10mg)pkg of 1 × 5 mg (860654P-5mg)
manufacturer/tradename
Avanti Polar Lipids 860654P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCC
InChI
1S/C17H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h16-17,19-20H,2-15,18H2,1H3/t16-,17+/m0/s1
InChI key
KFQUQCFJDMSIJF-DLBZAZTESA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
32164-02-6 | D-erythro-sphinganine (C17 base) | -- | ₹ 10,235.00 |
Related Products
Description
- General description: Sphinganine (d17:0), also referred to as dihydrosphingosine, is devoid of double bond.[1] Decarboxylating condensation of serine with palmitoyl-CoA yield keto intermediate(2-oxosphinganine), which is then reduced by NADPH to form Sphinganine.[2]
- Application: Sphinganine (d17:0) has been used in liquid chromatography-mass spectrometry (LC-MS) for the in-situ estimation of dihydrosphingosine utilization in N-(4-hydroxyphenyl)retinamide (4-HPR) resistant leukemia cells.[3] It is suitable for use as an internal standard in metabolomic study.[4]
- Biochem/physiol Actions: Sphinganine (SPA) or D-erythro-sphinganine is involved in sphingolipid biosynthesis pathway.[1] It acts as a precursor for ceramide.[2] SPA has an ability to inhibit the activity of protein kinase c. SPA accumulation enables fumonisin B1 to stimulate apoptosis.[5] It also has an ability to block cholesterol transport in Niemann-Pick Type C (NPC) disease.[6]
- Packaging: 5 mL Amber Glass Screw Cap Vial (860654P-10mg)
SAFETY INFORMATION
WGK
WGK 3