860815P
16:0(2R-OH) Ceramide
Manufacturer: Sigma Aldrich
CAS Number: 34839-02-6
Synonym(S): N-(2′-(R)-hydroxypalmitoyl)-D-erythro-sphingosine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 860815P-5-MG | In Stock | ₹ 38,970.00 |
860815P - 5 MG
In Stock
Quantity
1
Base Price: ₹ 38,970.00
GST (18%): ₹ 7,014.60
Total Price: ₹ 45,984.60
form
powder
packaging
pkg of 1 × 25 mg (860815P-25mg)pkg of 1 × 5 mg (860815P-5mg)
manufacturer/tradename
Avanti Polar Lipids 860815P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCC)=O)CO
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
34839-02-6 | N-(2'-(R)-hydroxypalmitoyl)-D-erythro-sphingosine | -- | ₹ 1,24,689.00 |
Related Products
Description
- General description: Ceramides with 2-hydroxy fatty acids (hFA) group are present in the epidermis.[1] 16:0(2R-OH) Ceramide is a unique ceramide containing 16C long chain base fatty acid (palmitic acid)-with 2′-hydroxyl group in R configuration.[2]
- Biochem/physiol Actions: Hydroxy fatty acid (hFA)-sphingolipids are implicated in cell signaling.[3] They may also help in regulation of cell differentiation and apoptosis. Synthetic 2′R-hydroxy-C16-ceramide exhibits high proapoptotic activity than proapoptotic 2′S-hydroxy-C16-ceramide.[2] hFA-ceramides in epidermis support permeability barrier function. hFA-ceramides are synthesized by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H causes neurological disorders including, leukodystrophy and spastic paraparesis in humans.[3] The mechanism of action for an antitumor drug, PM02734 involves hFA-ceramides in the cell membrane.[4]
- Packaging: 5 mL Amber Glass Screw Cap Vial (860815P-25mg)
SAFETY INFORMATION
WGK
WGK 3