860820P

20:0(2S-OH) Ceramide

Manufacturer: Sigma Aldrich

CAS Number: 1246298-48-5

Synonym(S): N-(2′-(S)-hydroxyarachidoyl)-D-erythro-sphingosine

Select a Size

Pack Size SKU Availability Price
5 MG 860820P-5-MG In Stock ₹ 38,970.00

860820P - 5 MG

₹ 38,970.00

In Stock

Quantity

1

Base Price: ₹ 38,970.00

GST (18%): ₹ 7,014.60

Total Price: ₹ 45,984.60

form

powder

packaging

pkg of 1 × 5 mg (860820P-5mg)

manufacturer/tradename

Avanti Polar Lipids 860820P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCCCCCCCCCC)=O)CO

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Description

  • General description: Ceramides linked to 2-hydroxy fatty acids (hFA) are present in the surface epithelium of the skin.[1] 20:0(2S-OH) Ceramide is a unique ceramide containing 20C long chain base fatty acid (arachidic acid)-with 2′-hydroxyl group in S configuration.[2]
  • Biochem/physiol Actions: Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling,[3] cell differentiation and apoptosis.[4] In epidermis, hFA-ceramides aid in permeability barrier function.[3] NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides.[2] FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans.[3] hFA-ceramides help PM02734 (elisidepsin),[5] an antitumor drug to exhibit its activity.[3]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860820P-5mg)

SAFETY INFORMATION

WGK

WGK 3