KRN7000
Manufacturer: Sigma Aldrich
CAS Number: 158021-47-7
Synonym(S): α-Galactosyl Ceramide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | 867000P-1-MG | In Stock | ₹ 37,162.23 |
867000P - 1 MG
In Stock
Quantity
1
Base Price: ₹ 37,162.23
GST (18%): ₹ 6,689.201
Total Price: ₹ 43,851.431
form
powder
packaging
pkg of 1 × 1 mg (867000P-1mg)
manufacturer/tradename
Avanti Polar Lipids
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCCCC)=O)CO[C@@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O
InChI
1S/C50H99NO9/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-25-26-27-29-31-33-35-37-39-45(54)51-42(41-59-50-49(58)48(57)47(56)44(40-52)60-50)46(55)43(53)38-36-34-32-30-28-16-14-12-10-8-6-4-2/h42-44,46-50,52-53,55-58H,3-41H2,1-2H3,(H,51,54)/t42?,43-,44-,46+,47+,48+,49-,50+/m1/s1
InChI key
VQFKFAKEUMHBLV-VDYNBUGPSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Medchemexpress LLC HY-102022 1mg , α-Galactosylceramide CAS:158021-47-7 Purity:>98% | -- | ₹ 46,725.00 | ||
Enzo Life Sciences KRN7000 (100 µg). CAS: 158021-47-7 | -- | ₹ 39,507.10 | ||
Enzo Life Sciences KRN7000 (1 mg). CAS: 158021-47-7 | -- | ₹ 1,25,098.40 | ||
Sigma Aldrich Fine Chemicals Biosciences (2S,3S,4R)-1-O-(alpha-D-Galactosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol >=95% (TLC) | 158021-47-7 | MFCD00939559 | 1MG | -- | ₹ 1,18,672.60 | ||
(2S,3S,4R)-1-O-(α-D-Galactosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol | -- | ₹ 71,336.75 | ||
158021-47-7 | N-[(1S,2S,3R)-1-[(α-D-Galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]hexacosanamide | -- | ₹ 13,261.00 |
Related Products
Description
- General description: α-Galactosyl Ceramide (KRN7000) is a high affinity glycolipid ligand for invariant natural killer T cell (iNKT).[1] It has α-galactosyl ceramide core and is a variant of agelasphin-9b ceramide core.[2] It is a synthetic homolog of α‐GalCer from marine sponges.[3] It comprises long fatty acyl chain (C26) and sphingosine base (C18).[4]
- Application: α-Galactosyl Ceramide (KRN7000) has been used in the in-vitro stimulation of natural killer cells.[5] It is suitable for use as a lipid antigen in bone marrow derived cells (BMDC) and hepatocyte primary cells prior to antigen presentation assay.[6] It is also suitable for use as a ligand invariant natural killer T cell activation.[1]
- Biochem/physiol Actions: α-Galactosyl Ceramide (KRN7000) administration results in T helper (TH0) or TH2 cytokine response.[3] it displays potent antitumor activity in various in vivo models such as B6 melanoma, colon26 adenocarcinoma and hepatic metastases.[4]
- Packaging: 5 mL Amber Glass Screw Cap Vial (867000P-1mg)
- Other Notes: Not available in Japan
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable