999995P
Edelfosine
Manufacturer: Sigma Aldrich
CAS Number: 77286-66-9
Synonym(S): 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 999995P-10MG | 999995P-999995P-10MG | In Stock | ₹ 15,414.80 |
| 999995P-50MG | 999995P-999995P-50MG | In Stock | ₹ 59,028.73 |
999995P - 999995P-10MG
In Stock
Quantity
1
Base Price: ₹ 15,414.80
GST (18%): ₹ 2,774.664
Total Price: ₹ 18,189.464
form
powder
packaging
pkg of 1 × 5 mg (999995P-5mg)
manufacturer/tradename
Avanti Polar Lipids 999995P
lipid type
cardiolipinsphospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC)COCCCCCCCCCCCCCCCCCC)=O
InChI
1S/C10H24NO5P/c1-6-10(14-5)9-16-17(12,13)15-8-7-11(2,3)4/h10H,6-9H2,1-5H3/t10-/m0/s1
InChI key
GVMCXWJIRSIWFJ-JTQLQIEISA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
77286-66-9 | (R)-2-Methoxy-3-(octadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate | -- | ₹ 37,380.00 |
Related Products
Description
- Application: Edelfosine or 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine might be used:as a non-hydrolysable LysoPC (phospholipid) analog for analyzing its ability to block sexual commitment in Plasmodium falciparum[1]in multilamellar vesicle preparation, to study its effect on model membranes[2]in the selection and screening of mutagenized cells, having the ability to inhibit the transport of alkylphosphocholine drugs across the plasma membrane[3]
- Biochem/physiol Actions: Edelfosine acts as a precursor for alkyl-lysophospholipids. It possesses apoptotic action against several cancer cells such as prostate, leukemia, brain and lung tumors. It is associated with cellular transport system, signaling transducing systems, cytokine synthesis and lipid metabolism. Edelfosine is known to control intracellular calcium levels. It is not mutagenic[2] and its anti-tumor action requires its incorporation into the cell.[4] Edelfosine is also found to block the replication of human immunodeficiency virus type I (HIV-I).[2]
- Packaging: 5 mL Clear Glass Sealed Ampule (999995P-5mg)
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable