C4895

Cephalexin hydrate

first-generation cephalosporin antibiotic

Manufacturer: Sigma Aldrich

CAS Number: 1820673-23-1

Select a Size

Pack Size SKU Availability Price
5 G C4895-5-G In Stock ₹ 15,479.75
10 G C4895-10-G In Stock ₹ 29,032.65
25 G C4895-25-G In Stock ₹ 51,624.43

C4895 - 5 G

₹ 15,479.75

In Stock

Quantity

1

Base Price: ₹ 15,479.75

GST (18%): ₹ 2,786.355

Total Price: ₹ 18,266.105

Quality Level

200

form

powder

pKa

5.27.3

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteria

Mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

InChI

1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15?;/m1./s1

InChI key

AVGYWQBCYZHHPN-FNOHQHCYSA-N

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Description

  • General description: Chemical structure: ß-lactam
  • Application: Cephalexin is a cephalosporin antibiotic used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
  • Biochem/physiol Actions: Cephalexin disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cephalexin antibiotics mimic the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan.
  • Other Notes: Storage of this product should be in airtight containers and protected from light.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Precautionary Statements

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves