C6880

D-Cycloserine

Manufacturer: Sigma Aldrich

CAS Number: 68-41-7

Synonym(S): (R)-4-Amino-3-isoxazolidone, 4-Amino-3-isoxazolidinone

Select a Size

Pack Size SKU Availability Price
1 G C6880-1-G In Stock ₹ 7,739.88
5 G C6880-5-G In Stock ₹ 27,246.53

C6880 - 1 G

₹ 7,739.88

In Stock

Quantity

1

Base Price: ₹ 7,739.88

GST (18%): ₹ 1,393.178

Total Price: ₹ 9,133.058

form

powder

Quality Level

200

mp

147 °C (dec.) (lit.)

antibiotic activity spectrum

Gram-negative bacteriamycobacteria

Mode of action

cell wall synthesis | interferes

storage temp.

−20°C

SMILES string

N[C@@H]1CONC1=O

InChI

1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1

InChI key

DYDCUQKUCUHJBH-UWTATZPHSA-N

Gene Information

human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444) , GRINA(2907) mouse ... GRIN1(14810) , GRIN2A(14811) , GRIN2B(14812) , GRIN2C(14813) , GRIN2D(14814) , GRIN3A(242443) , GRIN3B(170483) , GRINA(66168) rat ... GRIN1(24408) , GRIN2A(24409) , GRIN2B(24410) , GRIN2C(24411) , GRIN2D(24412) , GRIN3A(191573) , GRIN3B(170796) , GRINA(266668)

Other Options

Image Product Name Manufacturer Price Range
Sigma Aldrich Fine Chemicals Biosciences D-Cycloserine | 68-41-7 | MFCD00005353 | 1G
-- ₹ 10,291.96
Medchemexpress LLC HY-B0030 500mg Medchemexpress, D-Cycloserine CAS:68-41-7 Purity:>98%
-- ₹ 6,541.50
Chem-Impex International, Inc. D-Cycloserine | 68-41-7 | MFCD00005353 | 5G
-- ₹ 4,564.81
Chem-Impex International, Inc. D-Cycloserine, synthetic | 68-41-7 | MFCD00005353 | 1G
-- ₹ 3,003.75
Cycloserine
-- ₹ 11,647.70
D-Cycloserine
-- ₹ 6,743.98 - ₹ 91,666.10
D-Cycloserine
-- ₹ 7,739.88 - ₹ 27,246.53
D-Cycloserine
-- ₹ 6,743.98 - ₹ 91,666.10
D-Cycloserine
-- ₹ 445.00 - ₹ 42,987.00
68-41-7 | (4R)-4-amino-1,2-oxazolidin-3-one
-- ₹ 1,424.00 - ₹ 41,474.00

Related Products

Img

Sigma Aldrich

A9393

anhydrous, 96.0-102.0% (anhydrous b...

Img

Sigma Aldrich

A6140

900-1050 μg/mg anhydrous basis (HPL...

Img

Sigma Aldrich

A8523

95.0-102.0% anhydrous basis...

Img

Sigma Aldrich

D1822

--

Img

Sigma Aldrich

C7912

potency: 916-964 μg per mg...

Img

Sigma Aldrich

C0378

≥98% (HPLC)...

Img

Sigma Aldrich

A7926

--

Img

Sigma Aldrich

C9231

meets USP testing specifications...

Description

  • General description: Chemical structure: amino acid derivatives
  • Application: D-Cycloserine (DCS) has been used:to study its effect on partner preference in Prairie Voles[1]to study its effect on grooming behaviour of rats[2]to determine its minimum inhibitory concentration (MIC) on 48 multidrug resistant tuberculosis (MDR-TB) isolates using the broth microdilution method[3]to study its effect on mouse model of autism, using behavioural assays[4]
  • Biochem/physiol Actions: D-cycloserine (DCS) was initially known as a tuberculostatic agent. It acts as a glutamatergic partial N-methyl-D-aspartate (NMDA) agonist. It binds at the glycine-binding site of the NMDA receptor and enable the opening of the NMDA channel.[5] DCS has a an ability to improve various forms of learning and memory hence, this drug might be effective for improving social memory and cognition.[1] DCS can be used as a potential therapeutic for psychiatric disorders such as phobias, social anxiety, obsessive-compulsive disorder, and posttraumatic stress disorder.[6]

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves