D3897

2′-Deoxycytidine

≥99% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 951-77-9

Synonym(S): Cytosine deoxyriboside

Select a Size

Pack Size SKU Availability Price
100 MG D3897-100-MG In Stock ₹ 3,150.08
250 MG D3897-250-MG In Stock ₹ 4,882.08
500 MG D3897-500-MG In Stock ₹ 7,978.03
1 G D3897-1-G In Stock ₹ 12,762.68
5 G D3897-5-G In Stock ₹ 44,057.75

D3897 - 100 MG

₹ 3,150.08

In Stock

Quantity

1

Base Price: ₹ 3,150.08

GST (18%): ₹ 567.014

Total Price: ₹ 3,717.094

biological source

synthetic (organic)

Quality Level

200

Assay

≥99% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

storage temp.

−20°C

SMILES string

NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2

InChI

1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1

InChI key

CKTSBUTUHBMZGZ-SHYZEUOFSA-N

Description

  • General description: 2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides containing cytosine as the nucleobase. It is found in the blood, feces, and urine.[1]
  • Application: 2′-Deoxycytidine has been used:as a substrate for Trypanosoma brucei cytidine deaminase (TbCDA) to measure its activity[2]as a standard in the isolation and quantification of metabolite levels in murine tumor interstitial fluid by liquid chromatography-mass spectrometry (LC–MS)[3]to study the role of autophagy in response to oncogenes and DNA replication stress[4]
  • Biochem/physiol Actions: 2′-Deoxycytidine (deoxyC) forms dCTP upon phosphorylation which is used to synthesis DNA via various DNA polymerases or reverse transcriptases. DeoxyC is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2′-deoxyuridine. DeoxyC is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK). DeoxyC serves as a potential head and neck cancer marker.[1]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves