D7321

Diosmetin

Manufacturer: Sigma Aldrich

CAS Number: 520-34-3

Synonym(S): 3′,5,7-Trihydroxy-4′-methoxyflavone, 4′-Methylluteolin, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one, Luteolin 4′-methyl ether

Select a Size

Pack Size SKU Availability Price
10 MG D7321-10-MG In Stock ₹ 9,168.78
100 MG D7321-100-MG In Stock ₹ 27,787.78

D7321 - 10 MG

₹ 9,168.78

In Stock

Quantity

1

Base Price: ₹ 9,168.78

GST (18%): ₹ 1,650.38

Total Price: ₹ 10,819.16

Assay

≥98% (HPLC)

Quality Level

200

form

powder

color

light yellow to yellow

solubility

DMSO: 1 mg/mL, clear, faintly yellow to greenish-yellow

application(s)

metabolomicsvitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O)cc3O2

InChI

1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3

InChI key

MBNGWHIJMBWFHU-UHFFFAOYSA-N

Description

  • General description: Diosmetin is a methylated aglycone flavone of diosmin.[1] It is present abundantly in citrus fruits, Olea europaea L. (olive tree) leaves[2], and in the legume of Acacia farnesiana tree.[1]
  • Application: Diosmetin has been used to test its protective effects on chronic stress memory and cognitive impairment in mice model.[2]
  • Biochem/physiol Actions: Diosmetin exhibits anti-inflammatory, anti-cancer, antimicrobial, phytoestrogenic, and neuroprotective properties.[2] It displays cytoprotective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by inhibiting nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome and activating nuclear factor erythroid 2–related factor 2 (Nrf2).[3]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable