L5793

Leupeptin

powder, ≥95% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 103476-89-7

Synonym(S): Leupeptin hemisulfate salt, Acetyl-Leu-Leu-Arg-al, N-Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate salt

Select a Size

Pack Size SKU Availability Price
5 MG L5793-5-MG In Stock ₹ 30,299.18
25 MG L5793-25-MG In Stock ₹ 81,003.48
100 MG L5793-100-MG In Stock ₹ 2,34,209.70

L5793 - 5 MG

₹ 30,299.18

In Stock

Quantity

1

Base Price: ₹ 30,299.18

GST (18%): ₹ 5,453.852

Total Price: ₹ 35,753.032

product name

Leupeptin, BioUltra, microbial, ≥95% (HPLC)

biological source

microbial

Quality Level

200

product line

BioUltra

Assay

≥95% (HPLC)

form

powder

solubility

H2O: 50 mg/mL

storage temp.

−20°C

SMILES string

OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O

InChI

1S/2C20H38N6O4.H2O4S/c2*1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;1-5(2,3)4/h2*11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H2,1,2,3,4)/t2*15-,16-,17-;/m00./s1

Related Products

Img

Sigma Aldrich

C9523

--

Img

Sigma Aldrich

30030

≥96% (HPLC)...

Img

Sigma Aldrich

S1270

synthetic, ≥95%...

Img

Sigma Aldrich

W4394

≥95% (HPLC)...

Description

  • Biochem/physiol Actions: Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.)
  • Analysis Note: Leupeptin gives multiple peaks on HPLC because of the formation of tautomeric isomers in solution. Majority of contaminating peptide is racemized leupeptin.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves