N5285

Neomycin trisulfate salt hydrate

meets USP testing specifications, powder

Manufacturer: Sigma Aldrich

CAS Number: 1405-10-3

Synonym(S): Framycetin sulfate, Neomycin Sulfate

Select a Size

Pack Size SKU Availability Price
25 G N5285-25-G In Stock ₹ 7,945.55
100 G N5285-100-G In Stock ₹ 18,532.40

N5285 - 25 G

₹ 7,945.55

In Stock

Quantity

1

Base Price: ₹ 7,945.55

GST (18%): ₹ 1,430.199

Total Price: ₹ 9,375.749

Agency

USP/NFmeets USP testing specifications

Quality Level

200

form

powder

solubility

H2O: 50 mg/mL (Stock solutions should be filter sterilized and stored at 2-8 °C. Stable at 37 °C for 5 days.)

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteria

application(s)

pharmaceutical (small molecule)

Mode of action

protein synthesis | interferes

SMILES string

O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@@H](O[C@@H]2CO)O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N)C(N)[C@@H](O)[C@@H]1O

InChI

1S/C23H46N6O13.3H2O4S.H2O/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;3*1-5(2,3)4;/h5-23,30-36H,1-4,24-29H2;3*(H2,1,2,3,4);1H2/t5-,6+,7-,8+,9-,10-,11?,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;;;;/m1..../s1

InChI key

WHAGUNPVKDUVFV-QGTTWHFQSA-N

Other Options

Image Product Name Manufacturer Price Range
TOKU-E Neomycin Sulfate, USP, 1405-10-3, 25 g
-- ₹ 5,090.80
TOKU-E Neomycin Sulfate, USP, 1405-10-3, 100 g
-- ₹ 9,612.00
TOKU-E Neomycin Sulfate, USP, 1405-10-3, 500 g
-- ₹ 41,563.00
Sigma Aldrich Fine Chemicals Biosciences Neomycin sulphate European Pharmacopoeia (EP) Reference Standard | 1405-10-3 |
-- ₹ 24,531.07
Enzo Life Sciences Neomycin . sulfate (25g). CAS: 1405-10-3
-- ₹ 46,262.20
Neomycin sulfate
-- ₹ 47,987.23
Neomycin sulfate, for microbiological assay
-- ₹ 16,107.60
Neomycin trisulfate salt hydrate
-- ₹ 2,673.78
Neomycin trisulfate salt hydrate
-- ₹ 28,274.90
Neomycin trisulfate salt hydrate
-- ₹ 3,734.63 - ₹ 23,230.45

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Description

  • General description: Chemical structure: aminoglycoside
  • Application: Neomycin Trisulfate is produced by Streptomyces containing a minimum of 85% neomycin B. It has been used as a selection agent for prokaryotic cells transformed using the neo selectable marker gene, and to study ototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts, and extraction of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins. It is recommended for use in cell culture applications at 50 mg/L.
  • Biochem/physiol Actions: Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria.
  • Caution: Stock solutions should be filter sterilized and stored at 2-8°C, and are stable at 37°C for 5 days. A 1 mg/mL neomycin solution in .1 M phosphate buffer, pH 8.0 should be used within 14 days when stored at 0-5°C. Solutions should be protected from light or moisture.
  • Preparation Note: Neomycin sulfate is soluble in H2O at 50 mg/mL, yielding a clear solution.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Precautionary Statements

P261 - P280 - P342 + P311

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves