P5396
Phosphomycin disodium salt
antibacterial MurA inhibitor
Manufacturer: Sigma Aldrich
Synonym(S): (−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, Fosfomycin, Phosphonomycin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | P5396-1-G | In Stock | ₹ 4,838.78 |
| 5 G | P5396-5-G | In Stock | ₹ 12,773.50 |
| 50 G | P5396-50-G | In Stock | ₹ 52,068.25 |
P5396 - 1 G
In Stock
Quantity
1
Base Price: ₹ 4,838.78
GST (18%): ₹ 870.98
Total Price: ₹ 5,709.76
Quality Level
200
form
powder
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteria
Mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[Na+].[Na+].C[C@@H]1O[C@@H]1P([O-])([O-])=O
InChI
1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1
InChI key
QZIQJIKUVJMTDG-JSTPYPERSA-L
Related Products
Description
- Application: Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections. It is used for susceptibility studies of Klebsiella pneumoniae[1] and to study in vitro susceptibility testing procedures for fosfomycin tromethamine[2].
- Biochem/physiol Actions: Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.
- Other Notes: 1g,5g,50g
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves