P6188

Prostaglandin I2 sodium salt

≥96% (HPLC), synthetic, powder

Manufacturer: Sigma Aldrich

CAS Number: 61849-14-7

Synonym(S): (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt, Epoprostenol sodium salt, PGI2-Na, Prostacyclin sodium salt

Select a Size

Pack Size SKU Availability Price
1 MG P6188-1-MG In Stock ₹ 43,711.35
5 MG P6188-5-MG In Stock ₹ 1,21,954.45
10 MG P6188-10-MG In Stock ₹ 1,74,109.30

P6188 - 1 MG

₹ 43,711.35

In Stock

Quantity

1

Base Price: ₹ 43,711.35

GST (18%): ₹ 7,868.043

Total Price: ₹ 51,579.393

biological source

synthetic

Quality Level

200

Assay

≥96% (HPLC)

form

powder

color

white to off-white

solubility

H2O: 1 mg/mL (Hydrolyzes to 6-ketoprostaglandin F1α in aqueous solution.)ethanol: 50 mg/mL

functional group

carboxylic acidhydroxyl

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@](O/2)([H])[C@]1([H])CC2=C\CCCC(O)=O.[Na]

Related Products

Img

Sigma Aldrich

P0424

≥99%, synthetic, powder...

Img

Sigma Aldrich

P7527

powder, γ-irradiated, BioXtra, suit...

Img

Sigma Aldrich

LM1504

--

Img

Sigma Aldrich

P6888

≥95% anhydrous basis...

Img

Sigma Aldrich

L7877

≥95% (HPLC)...

Img

Sigma Aldrich

M6876

≥97.0% dry basis (enzymatic)...

Img

Sigma Aldrich

O6754

≥97% (TLC), oil...

Description

  • Application: Prostaglandin I2 sodium salt has been used:in the preparation of stock solution for platelet washing procedure[1]as supplement in platelet-rich-plasma, for platelet preparation[2]to prevent platelet activation[3]
  • Biochem/physiol Actions: Prostacyclin is a short-lived product of the cyclooxygenase pathway in vascular endothelial cells. It is a potent inhibitor of platelet aggregation by antagonizing thromboxane A2 and stimulating platelet adenylyl cyclase.[4] Nitric oxide is also produced in vascular endothelium where it inhibits platelet aggregation, regulates inducible cyclooxygenase production, and may work synergistically with prostacyclin to attenuate the thrombotic process. Prostacyclin is vasoprotective, protecting arterial walls from injury-induced lesions and cytoprotective in the liver and gastrointestinal tract.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves