Rapamycin
from Streptomyces hygroscopicus, ≥95% (HPLC), powder, mTOR inhibitor
Manufacturer: Sigma Aldrich
CAS Number: 53123-88-9
Synonym(S): 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, AY 22989, Sirolimus
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | R0395-1-MG | In Stock | ₹ 41,925.23 |
R0395 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 41,925.23
GST (18%): ₹ 7,546.541
Total Price: ₹ 49,471.771
product name
Rapamycin from Streptomyces hygroscopicus, ≥95% (HPLC), powder
Quality Level
300
Assay
≥95% (HPLC)
form
powder
color
off-white
solubility
ethanol: 2 mMDMSO: soluble
antibiotic activity spectrum
fungiyeast
Mode of action
enzyme | inhibitsprotein synthesis | interferes
storage temp.
−20°C
SMILES string
CO[C@@H]1C[C@@H](CC[C@H]1O)C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Medchemexpress LLC HY-10219 200mg , Rapamycin CAS:53123-88-9 Purity:>98% | -- | ₹ 12,335.40 | ||
Medchemexpress LLC HY-10219 25mg , Rapamycin CAS:53123-88-9 Purity:>98% | -- | ₹ 5,139.75 | ||
Medchemexpress LLC HY-10219 2g , Rapamycin CAS:53123-88-9 Purity:>98% | -- | ₹ 71,769.60 | ||
Cayman Chemical Rapamycin, 53123-88-9, 25 mg | -- | ₹ 33,059.05 | ||
VETRANAL™ Rapamycin, MilliporeSigma™ Supelco™ | -- | ₹ 68,396.50 | ||
Lkt Laboratories CAS 53123-88-9, ≥99%. mTOR inhibitor produced by Streptomyces used to prevent rejection in organ transplant patients. It prevents IL-2-induced activation of T cells and B cells. | -- | ₹ 14,349.47 | ||
Medchemexpress LLC HY-10219 100mg Medchemexpress, Rapamycin CAS:53123-88-9 Purity:>98% | -- | ₹ 7,289.10 | ||
Sigma Aldrich Fine Chemicals Biosciences Rapamycin | 53123-88-9 |MFCD00867594 1mg | -- | ₹ 39,903.15 | ||
Cayman Chemical Rapamycin, 53123-88-9, 10 mg | -- | ₹ 14,124.30 | ||
Cayman Chemical Rapamycin, 53123-88-9, 5 mg | -- | ₹ 8,802.10 |
Related Products
Description
- General description: Chemical structure: macrolide
- Application: Rapamycin from Streptomyces hygroscopicus has been used: to treat BV2 cells or BV2-LC3 cells for autophagy assay[3]as an autophagy activator in the bone marrow mesenchymal stem cells (BM-MSCs) transfected with lentivirus carrier of small interfering RNA for FOXO3 (siFOXO3) to study the effects of Forkhead Box O3 (FOXO3) on the autophagy of BM-MSCs[4]to pre-incubate villi to inhibit the mammalian target of rapamycin complex 1 (mTORC1) signaling[5]
- Biochem/physiol Actions: A macrocyclic triene antibiotic that binds to and inhibits the molecular target of rapamycin (mTOR). It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). Rapamycin is a potent immunosuppressant and has anticancer activity.
- Features and Benefits: This compound is featured on the PKB/Akt page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
- Other Notes: Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Repr. 2
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves