Platycodin D
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 58479-68-8
Synonym(S): 3β-(β-D-glucopyranosyloxy)-2β,16α,23,24-tetrahydroxy-O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-olean-12-en-28-oic acid
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 MG | SMB00424-10-MG | In Stock | ₹ 34,087.93 |
| 50 MG | SMB00424-50-MG | In Stock | ₹ 1,20,384.83 |
SMB00424 - 10 MG
In Stock
Quantity
1
Base Price: ₹ 34,087.93
GST (18%): ₹ 6,135.827
Total Price: ₹ 40,223.757
Quality Level
200
Assay
≥98% (HPLC)
form
powder
application(s)
metabolomicsvitamins, nutraceuticals, and natural products
storage temp.
2-8°C
SMILES string
O[C@@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C(CO)(CO)[C@]3([H])CC[C@@]4(C)[C@]5(C)C[C@@H](O)[C@@]6(C(O[C@H]7[C@H](O[C@@H]8O[C@@H](C)[C@H](O[C@H]9[C@H](O)[C@@H](O[C@@H]%10OC[C@@](CO)(O)[C@H]%10O)[C@H](O)CO9)[C@@H](O)[C@H]8O)[C@@H](O)[C@@H](O
InChI
1S/C57H92O28/c1-23-40(81-45-39(72)41(30(64)18-76-45)82-49-43(73)56(75,21-61)22-78-49)36(69)38(71)46(79-23)83-42-33(66)29(63)17-77-48(42)85-50(74)57-12-11-51(2,3)14-27(57)24-7-9-52(4)26-13-28(62)44(84-47-37(70)35(68)34(67)31(16-58)80-47)55(19-59,20-60)25(26)8-10-54(52,6)53(24,5)15-32(57)65/h7,23,25-49,58-73,75H,8-22H2,1-6H3/t23-,25+,26-,27-,28-,29-,30+,31+,32+,33-,34+,35-,36-,37+,38+,39+,40-,41-,42+,43-,44-,45-,46-,47-,48?,49-,52+,53+,54+,56+,57+/m0/s1
InChI key
RJDYKSRQTBCKLC-XTIQGCOGSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Sigma Aldrich Fine Chemicals Biosciences Platycodin D >=98% (HPLC) | 58479-68-8 | 10MG | -- | ₹ 39,685.10 | ||
Sigma Aldrich Fine Chemicals Biosciences Platycodin D >=98% (HPLC) | 58479-68-8 | 50MG | -- | ₹ 1,35,475.80 | ||
Platycodin D | -- | ₹ 14,072.50 | ||
Platycodin D | -- | ₹ 58,097.78 | ||
58479-68-8 | Platycodin D | -- | ₹ 2,581.00 - ₹ 39,516.00 |
Description
- General description: Platycodin D (PD) is a triterpenoid saponin found in the root of Platycodon grandifloras called Platycodonis Radix.[1]
- Application: Platycodin D has been used:to test its anti-inflammatory and inhibitory effect on eosinophilic airway inflammation and T-helper type 2 (Th2) signaling pathways using ovalbumin (OVA)-induced allergic asthma mouse model[2]to test its anti-obese effects on the activation of brown adipose tissue featuring in vivo and in vitro studies[3]to test its efficacy as an adjuvant with infectious bronchitis (IB) vaccine in chicken[4]
- Biochem/physiol Actions: Platycodin D elicits strong anti-cancer properties and exhibits cytotoxicity against several cancer cell lines of both in vitro and in vivo origin.[1] It exerts anti-inflammatory and protective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by upregulating liver-X receptors α (LXRα) and ATP-binding cassette transporter A1 (ABCA1) signaling pathway.[5] It also possesses protective effects against Cisplatin (CDDP)-induced nephrotoxicity in mice.[6]
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable