T1895

Thymidine

powder, BioReagent, suitable for cell culture

Manufacturer: Sigma Aldrich

CAS Number: 50-89-5

Synonym(S): 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, 1-(2-Deoxy-β-D-ribofuranosyl)thymine, 2′-Deoxythymidine, Thymine deoxyriboside, dT

Select a Size

Pack Size SKU Availability Price
1 G T1895-1-G In Stock ₹ 4,900.00
5 G T1895-5-G In Stock ₹ 16,510.00
10 G T1895-10-G In Stock ₹ 27,939.33
25 G T1895-25-G In Stock ₹ 58,960.00

T1895 - 1 G

₹ 4,900.00

In Stock

Quantity

1

Base Price: ₹ 4,900.00

GST (18%): ₹ 882.00

Total Price: ₹ 5,782.00

biological source

synthetic (organic)

Quality Level

300

product line

BioReagent

Assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

mp

186-188 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless

SMILES string

CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O

InChI

1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1

Description

  • General description: Thymidine is also referred to as pyrimidine deoxynucleoside. Deoxythymidine is a nucleoside present in DNA. In a DNA double stranded structure, thymidine pairs with deoxyadeninosine.[1]
  • Application: Thymidine can be used in HT and HAT cocktails for hybridoma fusion, selection and cloning. It has been used:as a nucleotide source in minimal essential medium to evaluate the outgrowth of the iSCNT-derived blastocysts[2]as a supplement in Dulbecco′s Modified Eagle Medium (DMEM) selection medium used for the production of anti-neurogranin (NRGN) antibodies[3]to prepare THMG (thymidine, hypoxanthine, glycine, methotrexate) and THG stock solution for cleansing mouse lymphoma cells[4]
  • Biochem/physiol Actions: Thymidine is useful in cell synchronization during S-phase.[1] In the salvage pathway of pyrimidines, pyrimidine phosphorylase reversibly converts thymine to thymidine.[5]

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves