ALD00420

2-cyanophenyl sulfofluoridate

Manufacturer: Sigma Aldrich

Select a Size

Pack Size SKU Availability Price
500 MG ALD00420-500-MG In Stock ₹ 1,710.35

ALD00420 - 500 MG

₹ 1,710.35

In Stock

Quantity

1

Base Price: ₹ 1,710.35

GST (18%): ₹ 307.863

Total Price: ₹ 2,018.213

form

liquid

Quality Level

100

SMILES string

O=S(F)(OC1=CC=CC=C1C#N)=O

InChI

1S/C7H4FNO3S/c8-13(10,11)12-7-4-2-1-3-6(7)5-9/h1-4H

InChI key

FWHISILUCPTNBH-UHFFFAOYSA-N

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Description

  • General description: 2-Cyanophenyl sulfofluoridate is an aryl fluorosulfate. It undergoes Suzuki-Miyaura reaction with aryl boronic acid in the presence of Pd(OAc)2 and Et3N to afford the corresponding biaryl derivative. 2-Cyanophenyl sulfofluoridate can be synthesized from the reaction between phenol and sulfuryl fluoride in the presence of triethylamine.[1]
  • Application: The following aryl fluorosulfate can be utilized as a cross-coupling partner in Suzuki-Miyaura reactions. The standard reaction conditions for these palladium-catalyzed C-C bond formations are ligand-free and can be performed in water, at room temperatre and are not air sensitive.
  • Other Notes: Palladium-Catalyzed, Ligand-Free Suzuki Reaction in Water Using Aryl Fluorosulfates

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P280 - P304 + P340 + P312 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable