Description

• Application: DuPhos and BPE Ligands: Highly Efficient Privileged LigandsCatalyst for:Preparation of a key unit B precursor of cryptophycins via Horner-Wadsworth-Emmons reaction and asymmetric hydrogenationPreparation of constrained phenylalanine analogs via Heck reaction followed by asymmetric hydrogenation and cyclization stepsEnantioselective preparation of N-benzyloxy-β-amino acid Me esters by hydrogenation of α-(benzyloxyaminomethyl)acrylate stereoisomersPreparation of fluoro amino acids as synthons for potent macrocyclic HCV NS3 protease inhibitorsStereoselective preparation of triply isotope-labeled Ser, Cys, and AlaPreparation of β-amino acids from asymmetric hydrogenation of α-(aminomethyl)acrylatesAsymmetric hydrogenation of a-primary and secondary amino ketones and asymmetric synthesis of (-)-arbutamine and (-)-denopamine
• Legal Information: Sold in collaboration with Kanata Chemical Technologies Inc. for research purposes only. These compounds were made and sold under license from E.I. du Pont de Nemours and Company, which license does not include the right to use the compounds in producing products for sale in the pharmaceutical field.