906298
3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
Manufacturer: Sigma Aldrich
CAS Number: 952143-02-1
Synonym(S): Probe building block for photoaffinity labeling, Suzuki-Miyaura-compatible multifunctional photo probe building block, Trifluoromethyl diazirine aryl bromide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 906298-50-MG | In Stock | ₹ 22,440.23 |
906298 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 22,440.23
GST (18%): ₹ 4,039.241
Total Price: ₹ 26,479.471
Assay
≥95%
form
liquid
reaction suitability
reagent type: cross-linking reagent
storage temp.
2-8°C
SMILES string
BrC1=CC=C(C2(N=N2)C(F)(F)F)C=C1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
eMolecules Ambeed / 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine / 100mg / 716947519 / A136108 / / 952143-02-1 / [null] / 265.033 / C8H4BrF3N2 | -- | ₹ 11,135.68 | ||
3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine | -- | ₹ 7,565.00 - ₹ 1,44,180.00 | ||
952143-02-1 | 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine | -- | ₹ 8,366.00 |
Related Products
Description
- Application: 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine is a Suzuki-Miyaura (S−M)-compatible building block tailored for the design of photoaffinity probes (PAPs). Photoaffinity labeling (PAL) is of growing interest in chemical biology and drug discovery research for use in protein profiling; covalent inhibitors; protein-protein interactions and complexes; and target engagement, identification, or validation studies. Diazirines are desirable photoactivable groups for chemical probes; however, their installation is not always straightforward. In response, diazirine-tolerant S-M coupling conditions were developed by Ichiishi, et al, using 3-(4-bromophenyl)-3-(trifluoromethyl)-3H-diazirine and shown to be efficient and scalable with minimal perturbation of the diazirine.Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
- Other Notes: Reducing Limitation in Probe Design: The Development of a Diazirine-Compatible Suzuki-Miyaura Cross Coupling Reaction
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable