Description

• General description: Formic acid (HCOOH, FA) is the simplest carboxylic acid that is mostly found in insect bites and stings. It is widely utilized as a hydrogen storage molecule due to its low toxicity, recyclability, ease of usage, and liquid state in ambient conditions. [1]
• Application: Electrochemical CO(2) Reduction on Metallic and Oxidized Tin: This study uses grand-canonical density functional theory (DFT) and in situ attenuated total reflectance surface-enhanced infrared absorption spectroscopy (ATR-SEIRA) to investigate electrochemical carbon dioxide reduction on tin surfaces, where formic acid could play a role in understanding reaction mechanisms (Whittaker et al., 2024).Simultaneous Measurement of COVID-19 Treatment Drugs: This research demonstrates the use of UPLC-MS/MS for the simultaneous measurement of COVID-19 treatment drugs in rat plasma, indicating the importance of formic acid in preparing samples or as a mobile phase additive for better chromatographic separation (Zhou et al., 2024).Metabolite Profiling of Liquiritin: The study involves metabolite profiling using ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS), where formic acid is likely utilized in sample preparation or chromatographic processes (Chen et al., 2024).Analysis of Cocaine and Its Metabolites: This article explores solid-phase extraction followed by UHPLC-ESI-MS/MS analysis of cocaine metabolites, a method that often incorporates formic acid to enhance the ionization of analytes (Makhdoom et al., 2024).Determination of Antimicrobial Compounds in Pigs: This research uses UHPLC-MS/MS for the simultaneous determination of various antimicrobial compounds, demonstrating formic acid′s role in sample processing and chromatographic separation (Nowacka-Kozak et al., 2024).