36-331-0
Tocris Bioscience™ Adenosine 5'-(a,b-methylene)diphosphate sodium salt
Manufacturer: Tocris Bioscience™
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Purity
>98%
Quantity
10 mg
Molecular Weight (g/mol)
447.21
Gene Alias
AMPCP, APCP
Product Type
Adenosine 5'-(α,β-methylene)diphosphate sodium salt
Inhibitors
Adenosine 5'-(a,b-methylene)diphosphate sodium salt
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Description
- Adenosine 5'-(α,β-methylene)diphosphate sodium salt is an Ecto-5'-nucleotidase/CD73 inhibitor
- Blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine
- Reverses the doxorubicin-resistance in ecto-5'-nucleotidase-positive MDR cells (MCF7/A6 and L1210/A)
- Also increases rhodamine uptake and inhibits rhodamine efflux from ecto-5'-nucleotidase-positive MDR cells
- Vasoconstrictor.