200006990
Tocris Bioscience™ ML 162
Inhibits glutathione peroxidase (GPX4); induces ferroptosis
Manufacturer: Fischer Scientific
CAS Number: 1035072-16-2
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Chemical Name or Material
2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide
Target
Glutathione Peroxidase 4/GPX4
Purity
0.98
CAS
1035072-16-2
Molecular Formula
C23H22Cl2N2O3S
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ ML 162 | -- | ₹ 16,589.60 | ||
Tocris Bioscience™ ML 162 | -- | ₹ 67,506.50 | ||
Medchemexpress LLC HY-100002 5mg ,ML162 CAS:1035072-16-2 Purity:>98% | -- | ₹ 10,279.50 | ||
1035072-16-2 | α-[(2-chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thiopheneacetamide | -- | ₹ 2,314.00 - ₹ 14,062.00 |
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Description
- ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor
- It induces ferroptosis in vivo
- It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C