200009226

Tocris Bioscience™ Auxinole

Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system

Manufacturer: Fischer Scientific

CAS Number: 86445-22-9

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Chemical Name or Material

α-[2-(2,4-Dimethylphenyl)-2-oxoethyl]-1H-indole-3-acetic acid

Target

Molecular Glues

Purity

98%

CAS

86445-22-9

Molecular Formula

C20H19NO3

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ Auxinole
-- ₹ 13,234.30
Tocris Bioscience™ Auxinole
-- ₹ 55,714.00
86445-22-9 | AUXINOLE
-- ₹ 6,853.00 - ₹ 49,929.00

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Description

  • Auxinole is an auxin antagonist of TIR1/AFB receptors
  • Binds to TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and inhibit auxin-responsive gene expression
  • Auxinole competitively inhibits various auxin responses in planta
  • Auxinole also inhibits OsTIR1 that suppresses leaky degradation of degron-fused proteins
  • Can be used as a control compound with 5-Ph-IAA (Cat
  • No
  • 7392) in the AID2 degron system to switch off degradation.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C