200009247

Tocris Bioscience™ AP 1867

Selective binding ligand for FKBP12F36V

Manufacturer: Fischer Scientific

CAS Number: 195514-23-9

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Chemical Name or Material

(1R)-1-[3-(Carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl (2S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate

Target

TAG Degradation Platforms

Purity

98%

CAS

195514-23-9

Molecular Formula

C38H47NO11

Other Options

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Description

  • AP 1867 is a selective binding ligand for the single point mutant of FKBP12F36V (IC50 = 1.8 nM)
  • Functionalized with a carboxylic acid group at the meta-position to enable onward chemistry
  • The position of the carboxylic acid group represents an 'exit vector' allowing modification without interfering with the compound's binding ability.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C