45-185-0

Tocris Bioscience™ EPPTB

Manufacturer: Fischer Scientific

CAS Number: 1110781-88-8

Select a Size

Pack Size SKU Availability Price
Each of 1 45-185-0-Each-of-1 In Stock ₹ 92,916.00

45-185-0 - Each of 1

₹ 92,916.00

In Stock

Quantity

1

Base Price: ₹ 92,916.00

GST (18%): ₹ 16,724.88

Total Price: ₹ 1,09,640.88

Chemical Name or Material

N-(3-Ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)benzamide

Quantity

50 mg

Molecular Formula

C20H21F3N2O2

Purity

>99%

CAS

1110781-88-8

Target

Trace Amine 1 (TA1) Receptor Antagonists

Formula Weight

378.39

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ EPPTB
-- --
Tocris Bioscience™ EPPTB
-- ₹ 22,517.00
Sigma Aldrich Fine Chemicals Biosciences EPPTB >=95% (HPLC) | 1110781-88-8 | MFCD21605509 | 5MG
-- ₹ 11,230.02
eMolecules​ Medchem Express / Ro 5212773 / 5mg / 680109508 / HY-110098 / / 1110781-88-8 / MFCD21605509 / 378.395 / C20H21F3N2O2
-- ₹ 11,790.72
1110781-88-8 | EPPTB
-- ₹ 4,005.00 - ₹ 2,89,428.00

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Description

  • Trace amine 1 (TA1) receptor antagonist/inverse agonist; exhibits a higher potency at the mouse TA1 receptor than the rat and human TA1 receptors (IC50 values are 27.5, 4539 and 7487 nM, respectively)
  • Blocks the TA1 receptor-mediated activation of an inwardly rectifying K+ current, which increases the firing frequency of dopamine (DA) neurons in the ventral tegmental area
  • Increases DA potency at the D2 receptor
  • Also displays inverse agonism, reducing basal cAMP levels in vitro (IC50 = 19 nM).

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C