58-335-0
Tocris Bioscience™ Ex 26
Manufacturer: Fischer Scientific
CAS Number: 144678-63-7
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 58-335-0-Each-of-1 | In Stock | ₹ 1,00,926.00 |
58-335-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,00,926.00
GST (18%): ₹ 18,166.68
Total Price: ₹ 1,19,092.68
Chemical Name or Material
1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid
Quantity
10 mg
Molecular Formula
C28H28ClFN2O3
Physical Form
Solid
Product Type
Bioactive Small Molecule
CAS
144678-63-7
Solubility
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight
494.98
Color
White
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Ex 26 | -- | -- | ||
Tocris Bioscience™ Ex 26 | -- | ₹ 24,208.00 | ||
Tocris Bioscience™ NSC 668036 | -- | -- | ||
Tocris Bioscience™ NSC 668036 | -- | ₹ 20,781.50 | ||
Tocris Bioscience™ NSC 668036 | -- | ₹ 87,175.50 | ||
144678-63-7 | (2S)-N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanyl-2-hydroxy-3-methyl-butanoicAcid | -- | ₹ 3,026.00 - ₹ 31,862.00 |
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Description
- Potent and selective S1P1 receptor antagonist (IC50 = 0.93 nM)
- Exhibits > 3,000-fold selectivity for S1P1 over S1P2, S1P3, S1P4 and S1P5
- Induces lymphocyte sequestration in peripheral lymph nodes and upregulates S1P1 receptor expression
- Reduces disease severity in mice with EAE
- Increases IFN-α production in stimulated dendritic cells in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at 4°C