59-315-0

Tocris Bioscience™ PF 05089771

Manufacturer: Fischer Scientific

CAS Number: 1430806-04-4

Select a Size

Pack Size SKU Availability Price
Each of 1 59-315-0-Each-of-1 In Stock ₹ 95,853.00

59-315-0 - Each of 1

₹ 95,853.00

In Stock

Quantity

1

Base Price: ₹ 95,853.00

GST (18%): ₹ 17,253.54

Total Price: ₹ 1,13,106.54

Chemical Name or Material

4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate

Quantity

50 mg

Molecular Formula

C18H12Cl2FN5O3S2.C7H8O3S

Purity

>98%

CAS

1430806-04-4

Target

Voltage-gated Sodium Channel Blockers

Formula Weight

672.56

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ PF 05089771
-- --
Tocris Bioscience™ PF 05089771
-- ₹ 23,184.50
1430806-04-4 | 4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamidetosylate
-- ₹ 7,476.00 - ₹ 93,094.00

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Description

  • Potent and selective Nav1.7 channel blocker (IC50 = 8, 11 and 171 nM for mouse, human and rat Nav1.7, respectively)
  • Exhibits selectivity for Nav1.7 over other Nav1 channels (IC50 values are 0.11, 0.16, 0.85, 10, 11 and 25 μM for Nav1.2, Nav1.6, Nav1.1, Nav1.4, Nav1.3 and Nav1.5, respectively)
  • Also exhibits selectivity over a panel of 81 other ion channels, receptors, enzymes and transporters
  • Blocks spontaneous firing of inherited erythromelalgia (IEM)-derived iPSC sensory neurons in vitro .

SAFETY INFORMATION

  • Recommended Storage : Desiccate at Room Temperature