61-285-0

Tocris Bioscience™ GSK 343

Manufacturer: Tocris Bioscience™

CAS Number: 1346704-33-3

Select a Size

Pack Size SKU Availability Price
Each of 1 61-285-0-Each-of-1 In Stock ₹ 94,340.00

61-285-0 - Each of 1

₹ 94,340.00

In Stock

Quantity

1

Base Price: ₹ 94,340.00

GST (18%): ₹ 16,981.20

Total Price: ₹ 1,11,321.20

Chemical Name or Material

N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1H-indazole-4-carboxamide

Assay Percent Range

>98%

Molecular Formula

C31H39N7O2

CAS

1346704-33-3

Quantity

50 mg

Formula Weight

Observed MW: 541.69

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Description

  • Description GSK 343 is a potent and selective SAM-competitive EZH2 inhibitor (IC50 = 4 nM), that exhibits >60 fold selectivity for EZH2 over EZH1 and a range of other methyltransferases
  • GSK 343 decreases H3K27me3 levels in breast cancer cells and inhibits proliferation of prostate cancer cell lines in vitro .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C