64-335-0

Tocris™ GSK 1016790A

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 64-335-0-Each-of-1 In Stock ₹ 1,16,145.00

64-335-0 - Each of 1

₹ 1,16,145.00

In Stock

Quantity

1

Base Price: ₹ 1,16,145.00

GST (18%): ₹ 20,906.10

Total Price: ₹ 1,37,051.10

Quantity

50 mg

Formula Weight

655.61

Purity

98%

Molecular Formula

C28H32Cl2N4O6S2

Product Type

Agonist

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Description

  • Description GSK 1016790A is a potent TRPV4 agonist; elicits Ca2+ influx in human and mouse TRPV4-expressing HEK cells (EC50 values of 2.1 and 18 nM, respectively)
  • Enhances insulin mRNA expression
  • Increases ERK1/2 phosphorylation and NO production
  • Exhibits no activity at TRPM8 and TRPA1 (20 μM) channels
  • Induces bladder overactivity in TRPV4+/+ mice.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C