64-435-0
Tocris Bioscience™ IU1-47
Manufacturer: Tocris Bioscience™
CAS Number: 670270-31-2
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Chemical Name or Material
1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)ethanone
Quantity
50 mg
Formula Weight
330.85
CAS
670270-31-2
Molecular Formula
C19H23ClN2O
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
eMolecules IU1-47 | 670270-31-2 | MFCD03761987 | 5mg | -- | ₹ 11,529.06 | ||
Medchemexpress LLC HY-122243 5mg Medchemexpress, IU1-47 CAS:670270-31-2 Purity:>98% | -- | ₹ 14,017.50 | ||
670270-31-2 | 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(piperidin-1-yl)ethan-1-one | -- | ₹ 12,193.00 |
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Description
- IU1-47 is a potent USP14 inhibitor (IC50 = 60 nM)
- Demonstrates >30-fold selectivity for USP14 over USP5 (IsoT)
- Enhances degradation of proteasome substrates in vitro
- Increases degradation of wild type and pathological tau in MEFs, primary neuronal cultures and human iPSC derived neurons.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C