64-601-0
Tocris Bioscience™ ABX 464
Manufacturer: Fischer Scientific
CAS Number: 1258453-75-6
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 64-601-0-Each-of-1 | In Stock | ₹ 21,577.16 |
64-601-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 21,577.16
GST (18%): ₹ 3,883.889
Total Price: ₹ 25,461.049
Chemical Name or Material
8-Chloro-N-[4-(trifluoromethoxy)phenyl]-2-quinolinamine
Quantity
10 mg
Molecular Formula
C16H10ClF3N2O
CAS
1258453-75-6
Target
DNA, RNA and Protein Synthesis Compounds
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ ABX 464 | -- | -- | ||
Tocris Bioscience™ ABX 464 | -- | ₹ 90,541.48 | ||
Medchemexpress LLC HY-100870 5mg Medchemexpress, ABX464 CAS:1258453-75-6 Purity:>98% | -- | ₹ 10,746.75 | ||
1258453-75-6 | ABX-464 | -- | ₹ 7,832.00 - ₹ 26,967.00 |
Related Products
Description
- ABX 464 is an HIV RNA splicing modulator; it selectively enhances the splicing of HIV RNA in infected human PBMCs and inhibits viral replication, with no global effect on cellular splicing
- ABX 464 inhibits replication of HIV strains harboring mutations associated with drug-resistance
- ABX 464 binds the cap binding complex (CBC) and upregulates miR-124 expression in vitro and decreases expression of miR-124 target genes, MCP-1, CXCL-1, SERPIN-E1 in macrophages
- It also decreases the number of Th17 cells, as well as IL-6 soluble receptor in CD4+ T cells
- In HIV infected humanized mice, treatment with ABX 464 reduces viral load
- Anti-inflammatory.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C