64-995-0
Tocris Bioscience™ MLN 4924
Manufacturer: Fischer Scientific
CAS Number: 905579-51-3
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 64-995-0-Each-of-1 | In Stock | ₹ 78,809.50 |
64-995-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 78,809.50
GST (18%): ₹ 14,185.71
Total Price: ₹ 92,995.21
Chemical Name or Material
[(1 S,2 S,4 R)-4-[4-[[(1 S)-2,3-Dihydro-1 H-inden-1-yl]amino]-7 H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamic acid ester
Quantity
50 mg
Molecular Formula
C21H25N5O4S
CAS
905579-51-3
Target
NEDD8 Activating Enzyme E1)
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ MLN 4924 | -- | -- | ||
Tocris Bioscience™ MLN 4924 | -- | ₹ 18,868.00 | ||
Apexbio Technology LLC MLN4924, 10mg. Cas: 905579-51-3 MFCD: MFCD17215201. NAE inhibitor | -- | ₹ 20,559.00 | ||
Apexbio Technology LLC MLN4924, 50mg. Cas: 905579-51-3 MFCD: MFCD17215201. NAE inhibitor | -- | ₹ 51,620.00 | ||
Ubpbio A cell-permeable and irreversible inhibitor of Nedd8-activating enzyme (NAE), CAS# 905579-51-3, >98% purity | -- | ₹ 14,329.00 | ||
Medchemexpress LLC HY-70062 1mg , Pevonedistat CAS:905579-51-3 Purity:>98% | -- | ₹ 5,607.00 | ||
Selleck Chemical LLC Pevonedistat (MLN4924) 2mg 905579-51-3 | -- | ₹ 15,699.60 | ||
Cayman Chemical Pevonedistat | 905579-51-3 | 443.5 g/mol | 10MG | -- | ₹ 17,194.80 | ||
Chemie Tek MLN4924 (PEVONEDISTAT), 905579-51-3, MFCD17215201, 5mg | -- | ₹ 7,120.00 | ||
Cayman Chemical MLN4924, 905579-51-3, 1 mg | -- | ₹ 5,090.80 |
Related Products
Description
- MLN 4924 (Tak 924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50 = 4.7 nM)
- MLN 4924 exhibits selectivity over closely related enzymes UAE, UBA6, SAE, and ATG7 (IC50 = 1.5, 1.8, 8.2, and >10 μM, respectively), and displays minimal activity at adenosine receptors and a panel of 12 cellular kinases
- MLN 4924 exhibits cyotoxicity in several human tumor-derived cell lines and causes liver damage in SD rats, when given with TNF-α
- It blocks the NEDD8 pathway causing DNA damage in mice bearing HCT-116 xenografts
- Cell permeable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C