69-621-0

Tocris™ JBJ-03-142-02

Manufacturer: Tocris™

CAS Number: 2068806-31-3

Select a Size

Pack Size SKU Availability Price
Each of 1 69-621-0-Each-of-1 In Stock ₹ 29,320.16

69-621-0 - Each of 1

₹ 29,320.16

In Stock

Quantity

1

Base Price: ₹ 29,320.16

GST (18%): ₹ 5,277.629

Total Price: ₹ 34,597.789

Chemical Name or Material

(4-Fluorophenyl)methyl N-[2-[(1-methyl-1 H-pyrazol-4-yl)amino]-4-pyrimidinyl]-N-[3-[(1-oxo-2-propen-1-yl)amino]phenyl]carbamate

Quantity

10 mg

Molecular Formula

C25H22FN7O3

Purity

98%

CAS

2068806-31-3

Target

EGF Receptor Inhibitors

Formula Weight

2323

Other Options

Image Product Name Manufacturer Price Range
JBJ-03-142-02
-- ₹ 20,559.00 - ₹ 59,363.00
2068806-31-3 | JBJ-03-142-02
-- ₹ 24,742.00 - ₹ 1,25,312.00

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Description

  • JBJ-03-142-02 is a highly potent epidermal growth factor receptor (EGFR) and ErbB2 (human epidermal growth factor receptor; HER2) inhibitor
  • Inhibits wild type and tumorgenic mutated receptors (exon 20 insertion; Ex20Ins)
  • Antiproliferative in vitro (IC50 values are 7.6, 30 - 95, 3.8 and 19 - 31 nM for Ba/F3 cells expressing wild type EGFR, EGFR with Ex20Ins mutation, wild type HER2 and HER2 with Ex20Ins mutation, respectively)
  • Also inhibits other common EGFR mutants
  • Antiproliferative in patient-derived lung cancer cell lines.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C