69-782-5

Tocris™ AZD 5363

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 69-782-5-Each-of-1 In Stock ₹ 69,776.00

69-782-5 - Each of 1

₹ 69,776.00

In Stock

Quantity

1

Base Price: ₹ 69,776.00

GST (18%): ₹ 12,559.68

Total Price: ₹ 82,335.68

Synonym

Capivasertib

Molecular Formula

C21H25ClN6O2

Product Type

Inhibitor

Quantity

25 mg

Formula Weight

428.92

Purity

98%

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Description

  • AZD 5363 is a potent pan-AKT inhibitor (IC50 values are 3, 7 and 7 nM for AKt 1, 2 and 3, respectively)
  • Also inhibits P70S6K, PKA, ROCK2 and ROCK1 (IC50 values are 6, 7, 60 and 470 nM, respectively)
  • Inhibits growth of tumor cell lines in vitro , particularly breast, endometrial, gastric, hematologic and prostate cancers
  • Inhibits growth of human tumor xenografts in mice
  • Enhances in vivo antitumor effects of Docetaxel (Cat
  • No
  • 4056) and Lapatinib (Cat
  • No
  • 6811)
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C