70-181-0

Tocris Bioscience™ CBR-470-1

Manufacturer: Fischer Scientific

CAS Number: 2416095-06-0

Select a Size

Pack Size SKU Availability Price
Each of 1 70-181-0-Each-of-1 In Stock ₹ 23,807.50

70-181-0 - Each of 1

₹ 23,807.50

In Stock

Quantity

1

Base Price: ₹ 23,807.50

GST (18%): ₹ 4,285.35

Total Price: ₹ 28,092.85

Chemical Name or Material

(3 R,4 S)-rel-4-[(4-Chlorophenyl)sulfonyl]tetrahydro-N-(2-methylpropyl)-3-thiophenamine-1,1-dioxide

Quantity

10 mg

Molecular Formula

C14H20ClNO4S2

CAS

2416095-06-0

Target

Nrf2 Activators

Purity

98%

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ CBR-470-1
-- --
Tocris Bioscience™ CBR-470-1
-- ₹ 99,858.00
Medchemexpress LLC HY-134205A 5mg Medchemexpress, CBR-470-1 CAS:2416095-06-0 Purity:>98%
-- ₹ 6,541.50
2416095-06-0 | CBR-470-1
-- ₹ 9,701.00 - ₹ 63,902.00

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Description

  • CBR-470-1 is a phosphoglycerate kinase 1 (PGK1) inhibitor
  • CBR-470-1 promotes accumulation of the reactive metabolites methylglyoxal (MGO) resulting in KEAP1 modification and dimerization, which in turn leads to activation of the Nrf2 transcriptional program
  • CBR-470-1 protects SH-SY5Y neuroblastoma cells from MPP+-induced cytotoxicity via the Keap1-Nrf2 cascade.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C