70-291-0
Tocris™ GX 201
Manufacturer: Tocris™
CAS Number: 1788071-27-1
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-291-0-Each-of-1 | In Stock | ₹ 34,754.50 |
70-291-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,754.50
GST (18%): ₹ 6,255.81
Total Price: ₹ 41,010.31
Chemical Name or Material
4-[[1-[[2-Chloro-5-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methoxy]-5-cyclopropyl-2-fluoro-N-(methylsulfonyl)benzamide
Quantity
10 mg
Molecular Formula
C25H27ClF4N2O4S
CAS
1788071-27-1
Target
Voltage-gated Sodium Channel Blockers
Purity
0.98
Related Products
Description
- GX 201 is a potent and selective Nav1.7 blocker (IC50 = 3.2 nM)
- Exhibits 10x selectivity for Nav1.7 over Nav1.1, Nav1.2, and Nav1.6 channels
- Displays prolonged residency time on the Nav1.7 channel
- Chronic dosing increases compound potency ∽10-fold and provides efficacy that persists after the compound has cleared from plasma
- Suppresses neuropathic pain in a mouse diabetic neuropathy model
- Analgesic.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C