70-705

Tocris Bioscience™ Mirabegron

Manufacturer: Fischer Scientific

CAS Number: 223673-61-8

Select a Size

Pack Size SKU Availability Price
Each of 1 70-705-Each-of-1 In Stock ₹ 10,537.60

70-705 - Each of 1

₹ 10,537.60

In Stock

Quantity

1

Base Price: ₹ 10,537.60

GST (18%): ₹ 1,896.768

Total Price: ₹ 12,434.368

Chemical Name or Material

2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide

Quantity

5 mg

Purity

98%

CAS

223673-61-8

Molecular Formula

C21H24N4O2S

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ Mirabegron
-- --
Tocris Bioscience™ Mirabegron
-- ₹ 40,272.50
Apexbio Technology LLC Mirabegron (YM178), 10mg. Cas: 223673-61-8 MFCD: MFCD11100356. Selective β3-adrenoceptor agonist
-- ₹ 16,465.00
Selleck Chemical LLC Mirabegron 5mg 223673-61-8 YM 178
-- ₹ 15,699.60
Mirabegron
-- ₹ 12,773.50
2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
-- ₹ 623.00 - ₹ 80,634.00
223673-61-8 | 2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide
-- ₹ 3,026.00 - ₹ 95,675.00

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Description

  • Potent and selective β3-adrenoceptor agonist (EC50 = 22.4 nM)
  • Displays >440-fold selectivity for β3 over β1 and β2 adrenoceptors
  • Increases cAMP concentration in CHO cells expressing human β3-adrenoceptor
  • Displays relaxant effect in ex vivo rat bladder muscle preparation precontracted with carbachol Decreases frequency of bladder contraction in rats
  • Also promotes browning of white adipose tissue, reduces body weight, and improves glucose tolerance and insulin sensitivity in mice fed a high fat diet.