7082180

Tocris Bioscience™ RBC8

RalA and RalB GTPase inhibitor

Manufacturer: Fischer Scientific

CAS Number: 361185-42-4

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Chemical Name or Material

Ras GTPase Inhibitors

Synonym

6-Amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)pyrano[2,3-c]pyrazole-5-carbonitrile

Molecular Formula

C25H20N4O3

Physical Form

Solid

Purity

>98%

CAS

361185-42-4

Solubility

Soluble to 100mM in DMSO

Formula Weight

424.45

Product Type

Bioactive Small Molecule

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Description

  • RalA and RalB GTPase inhibitor (EC50 ∽3.5 μM)
  • Inhibits the binding of Ral to RaLBP1
  • Exhibits no detectable inhibition of Ras or RhoA activity
  • Suppresses growth of xenograft tumors in mice
  • Cell permeable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C