7110804

Tocris Bioscience™ Oltipraz

Nrf2 activator

Manufacturer: Fischer Scientific

CAS Number: 64224-21-1

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Chemical Name or Material

4-Methyl-5-(2-pyrazinyl)-3H-1,2-dithiole-3-thione

Target

Nrf2 Modulators

Formula Weight

226.34

CAS

64224-21-1

Molecular Formula

C8H6N2S3

Purity

>99%

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Description

  • Nrf2 activator; activates Nrf, which binds to antioxidant response elements (AREs) and induces Phase-I and -II drug-metabolizing enzymes including CYP2B and NQO1
  • Also increases mRNA levels of multiple hepatic xenobiotic transporters
  • Elevates expression of genes encoding anti-oxidant and multidrug resistance-associated proteins
  • Displays chemopreventive activity.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C