7110819

Tocris Bioscience™ DC 260126

FFA1 (GPR40) antagonist

Manufacturer: Fischer Scientific

CAS Number: 346692-04-4

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Chemical Name or Material

N-(4-Butylphenyl)-4-fluorobenzenesulfonamide

Target

Free Fatty Acid Receptor Antagonists

Formula Weight

307.38

CAS

346692-04-4

Molecular Formula

C16H18FNO2S

Purity

>98%

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Description

  • Free fatty acid receptor 1 (FFA1/GPR40) antagonist
  • Inhibits FFA-induced increases in intracellular Ca2+ levels and suppresses palmitic acid potentiated glucose-stimulated insulin secretion in Min6 pancreatic β cells in vitro
  • Decreases serum insulin levels, improves insulin sensitivity and reduces the number of apoptotic pancreatic β cells in obese diabetic ( db/db ) rats.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C