7110829

Tocris Bioscience™ Cytosporone B

High affinity Nur77 agonist

Manufacturer: Fischer Scientific

CAS Number: 321661-62-5

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Chemical Name or Material

Ethyl 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetate

Target

Nuclear Receptor Agonists

Formula Weight

322.4

CAS

321661-62-5

Molecular Formula

C18H26O5

Purity

>98%

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Kainate agonist; excitant and neuro...

Description

  • Naturally occurring Nur77 (NR4A1) agonist (Kd = 8.52 x 10-7 M)
  • Induces apoptosis in gastric cancer cells in vitro
  • Increases blood glucose levels in fasting C57 mice and suppresses xenograft tumor growth
  • Also exhibits a potent antifibrotic effect in bleomycin-induced skin fibrosis in vivo .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C