7110904

Tocris Bioscience™ Akti-1/2

Potent and selective dual Akt1 and 2 inhibitor

Manufacturer: Fischer Scientific

CAS Number: 612847-09-3

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Chemical Name or Material

1,3-Dihydro-1-[1-[[4-(6-phenyl-1 H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2 H-benzimidazol-2-one

Synonym

Akt Inhibitor VIII

Molecular Formula

C34H29N7O

Purity

98%

CAS

612847-09-3

Target

Akt (Protein Kinase B) Inhibitors

Formula Weight

551.64

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ Akti-1/2
-- ₹ 94,429.00
Tocris Bioscience™ Akti-1/2
-- ₹ 23,184.50
Enzo Life Sciences Akt inhibitor VIII (1mg). CAS: 612847-09-3
-- ₹ 13,407.85
Enzo Life Sciences Akt inhibitor VIII (5mg). CAS: 612847-09-3
-- ₹ 22,619.35
612847-09-3 | AKTI-1/2
-- ₹ 4,450.00 - ₹ 90,869.00

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Description

  • Potent and selective dual Akt1 and 2 inhibitor (IC50 values are 50 and 210 nM, respectively)
  • Selective for Akt1 and 2 over a panel of other tyrosine and serine/threonine kinases
  • Sensitizes LnCaP cells to TRAIL (TNF-related apoptosis-inducing ligand) induced apoptosis
  • Also enhances CAR and TCR retroviral transduction of human T cells
  • Active in vivo .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C