7110922

Tocris Bioscience™ TGX 221

Potent and selective PI 3-kinase β inhibitor

Manufacturer: Fischer Scientific

CAS Number: 663619-89-4

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Chemical Name or Material

7-Methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one

Target

PI 3-Kinase Inhibitors

Formula Weight

364.44

CAS

663619-89-4

Molecular Formula

C21H24N4O2

Purity

>98%

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ TGX 221
-- ₹ 36,753.44
Tocris Bioscience™ TGX 221
-- ₹ 1,54,034.08
Medchemexpress LLC HY-10114 10mg , TGX-221 CAS:663619-89-4 Purity:>98%
-- ₹ 10,933.65
Selleck Chemical LLC TGX-221 5mg 663619-89-4
-- ₹ 15,699.60
663619-89-4 | 7-Methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one
-- ₹ 1,691.00 - ₹ 82,236.00

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Description

  • Potent and selective PI 3-kinase β inhibitor (IC50 values are 0.007, 0.1, 3.5 and 5 μM for the β, δ, γ and α isoforms, respectively)
  • Shows >1,000-fold selectively for PI 3-kinase β over a range of other kinases
  • Inhibits thrombus formation in animal models.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C