7110963
Tocris Bioscience™ LCB 03-0110 dihydrochloride
Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk
Manufacturer: Fischer Scientific
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Chemical Name or Material
3-[[2-[3-(4-Morpholinylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenol dihydrochloride
Molecular Formula
C24H23N3O2S.2HCl
Purity
>98%
Target
Src Family Kinase Inhibitors
Formula Weight
490.45
Related Products
Description
- Potent c-Src kinase inhibitor (IC50 = 1.3 nM)
- Also potent inhibitor of discoidin domain receptor 2 (DDR2) family tyrosine kinases, BTK and Syk
- Suppresses LPS-induced activation of macrophages and TGF-β1- induced activation of fibroblasts in vitro
- Also inhibits activation of macrophages and fibroblasts and suppresses scar formation in a wound healing model.
SAFETY INFORMATION
- Recommended Storage : Desiccate at Room Temperature