7116063

Ciliobrevin A

Hedgehog (Hh) pathway antagonist, inhibits ciliogenesis; also inhibits dynein

Manufacturer: Fischer Scientific

CAS Number: 302803-72-1

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Chemical Name or Material

2,4-Dichloro-α-(3,4-4-oxo-2(1H)-quinazolinylidene)-β-oxobenzenepropanenitrile

Assay Percent Range

>98%

Formula Weight

Observed MW: 358.18

CAS

302803-72-1

Molecular Formula

C17H9Cl2N3O2

Other Options

Image Product Name Manufacturer Price Range
Ciliobrevin A
-- ₹ 50,463.00
Ciliobrevin A
-- ₹ 13,554.70
Sigma Aldrich Fine Chemicals Biosciences HPI-4 >=98% (HPLC) | 302803-72-1 | MFCD01911757 | 25MG
-- ₹ 47,312.40
Sigma Aldrich Fine Chemicals Biosciences HPI-4 >=98% (HPLC) | 302803-72-1 | MFCD01911757 | 5MG
-- ₹ 15,045.45
302803-72-1 | Ciliobrevin a
-- ₹ 712.00 - ₹ 7,031.00

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Description

  • Hedgehog (Hh) pathway antagonist; blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo
  • Perturbs primary cilia formation; inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C